Product related variants such as size variants, charge variant, sequence variant are of great importance in assessing the biologics product quality and manufacture process consistency. 

Novabioassays has developed state-of-the-art analytical variant analysis workflow for sensitive and comprehensive protein variant analysis. Our multimodal and high-resolving chromatography/electrophoresis techniques with online/offline configuration to high resolution Mass spectrometry enable superior resolution and sensitivity for protein variant analysis.

Our protein variant focus methods include CIEF, CE-MS, native IEX-MS,native SEC-MS, native HIC MS, native HILIC MS and RPLC-MS.